US: A federal judge in San Francisco ruled December 7 that a patent for DNA analysis owned by Swiss biotechnology company Hoffman-La Roche was obtained by deliberately misleading the USPTO and is invalid. US District Judge Vaughn Walker upheld a challenge by Promega which argued that scientists got the patent in 1990 through false claims. Those scientists worked for Cetus, which sold rights to the patent to Hoffman La Roche in 1991. The patented substance is called Taq DNA Polymerase. Cetus inventors had convinced the patent office that they had a substance better than those developed in the 1980s. Hoffman-La Roche is appealing, and contends that the ruling invalidates the patent for only one form of Taq, and not for the more common and lucrative recombinant Taq.